Media Buffer Products
Unlock Higher Titers, Better Consistency, and True Manufacturing Confidence
BZ Yield+™ is BioZen’s advanced CHO fed-batch media system engineered for today’s fast-moving biopharmaceutical environment. Designed using contemporary process-development analytics and built on a foundation of chemically defined, animal-component–free ingredients, BZ Yield+™ delivers superior growth, high specific productivity, and predictable quality attributes across a wide range of CHO clones.
BZ Yield+™ CHO Fed-Batch Media & Feed System
A complete two-part system engineered for superior CHO performance.
1. Optimized amino acid ratios
2. Balanced lipid & cholesterol supplement
3. Stable vitamins & trace elements
4. Gln-free & peptone-free design
5. Optional HT (Hypoxanthine/Thymidine) compatibility
Scalability
Performance verified across:
Evaluated Across Multiple CHO Lineages
1. Shake flasks
2. 250 mL/500 mL bench-scale bioreactors
3. 1–5 L process development reactors
4. GMP-scale SUBs (up to 2000 L)
Custom Buffers & Solution Builder : Precisely Tailored for Your Application
Product Description
Proprietary CHO Fed-Batch Medium is a chemically defined, animal component–free formulation that contains no hydrolysates or components of unknown composition. The formulation has been developed using multivariate analysis of over 10,000 data points, incorporating performance, physical, regulatory, and safety design specifications.
This medium supports robust cell growth and high viability and is specifically designed for fed-batch applications. When used in conjunction with the corresponding proprietary feed supplement, it enables enhanced productivity and consistent performance.
The system is optimized for CHO GS cell lines, delivering superior performance across industrial bioprocessing conditions.
Upcoming Product Announcement
We are excited to introduce our upcoming addition to the product portfolio:
BZ Cell Culture Media
Designed to support high-performance cell growth and consistency, BZ Cell Culture Media is developed with advanced formulation standards to meet diverse research and bioprocessing needs.
– Optimized for superior cell viability and productivity
– Ensures reproducibility and scalability
– Suitable for a wide range of applications
Stay tuned for more details and launch updates!
Proven Performance – High Growth & High Titers
Developed to support industry-relevant CHO platforms, BZ Yield+ consistently delivers:
- Higher viable cell densities
- Improved recombinant protein titers
- Stable metabolic with reduced lactate/ammonia stress
-
Robust performance from
shake flask → bench → pilot → GMP scale
Chemically Defined & ACF (Animal Component Free)
- Absolutely no animal-derived components
- Eliminates variability related to undefined hydrolysates
- Enhances reproducibility and regulatory confidence
Designed by Applied Bioprocess Data Science
This yields a formulation that supports high productivity without compromising critical quality attributes (CQAs). BZ Yield+ incorporates multivariate analysis and component-impact modeling to correlate raw materials with:
- Doubling time
- Specific productivity (qP)
- Glycan patterns & charge variants
- By-product generation
Robust, Scalable Manufacturing
- Manufactured under stringent Quality Management System
- Multi-site redundancy for secure supply
- Available in dry powder and ready-to-use liquid formats
- Excellent solubility and fast preparation time